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    Cystic Fibrosis Miniatlas (English Edition)

    Por Luis Raúl Lépori MD

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    Advances in genetics have enabled the basic principles of inheritance to be unraveled, leading to a more detailed understanding of many of the mechanisms that make it possible for the body to function correctly. Furthermore, many factors underlying certain diseases have been brought to light.Cystic fibrosis is one of the diseases in which it has been possible to identify in detail the genetic disturbances related to the clinical manifestations. Although only a single gene is responsible for this condition, there are more than eight hundred mutations that cause different degrees of the disorder. The main systems affected are the respiratory and digestive tracts and, untreated, cystic fibrosis can lead to a series of life-threatening complications. However, there are a number of therapeutic options that considerably improve the prognosis in these patients from an early age.It is thus essential for professionals to keep their knowledge permanently up to date and for affected individuals and their families to understand the condition, its clinical course, and the factors that affect its prognosis. In order to promote these objectives and contribute to improving the quality of life of these patients, we present this book that contains the fundamental, up-to-date information on this disease.



    Table of contents:

    Anatomic, histological, and physiological fundaments
    Anatomy of the respiratory system
    Histology of the respiratory epithelium
    Physiology of the airways
    Anatomy of the digestive system
    Histology of the digestive tube
    Physiology of digestion
    Structure and function CFTC protein

    Cystic fibrosis
    Definition and epidemiology
    Genetic bases
    Pathophysiology
    Repercussion of cystic fibrosis on the respiratory tract
    Clinical manifestations of respiratory disease
    Principal respiratory infections in cystic fibrosis
    Repercussion of cystic fibrosis on the digestive tract
    Clinical manifestations of digestive disease
    Repercussion of cystic fibrosis on other organs and systems

    Diagnosis and treatment of cystic fibrosis
    Diagnosis of cystic fibrosis
    Complementary tests
    Neonatal screening
    Genetic counseling
    General approach to treatment
    Treatment of digestive disorders
    Treatment of respiratory disorders
    Treatment of respiratory infections
    Treatment of respiratory complications

    References
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